The 7th Microscopy Characterisation of Organic-Inorganic Interfaces (MCOII) meeting will return to an in-person format in 2023 and will be hosted for the first time in North America at McMaster University in Hamilton, Canada, home of the Canadian Centre for Electron Microscopy. The transatlantic scientific organizing team of Nadja V. Tarakina (MPIKG, Germany) and Kathryn Grandfield (McMaster University, Canada) have put together an exciting two-day programme. As usual, the first day will be more general, covering a broad range of microscopy approaches (correlative microscopy solutions, in-situ liquid microscopy methods, low-voltage electron microscopy and many more) in the context of imaging hybrid and soft matter. On the second day, a special Focus Lecture Series, entitled “Multi-dimensional and multiscale microscopy of organic-inorganic interface” will cover a more-detailed range of lectures on tomographic methods spanning light, X-ray and electron microscopy, as well as atom probe tomography and in situ electron microscopy/tomography. This conference will bring together world-leading experts in microscopy, highlighting the latest achievements, new opportunities and outstanding challenges in probing beam-sensitive and hybrid materials and their interfaces.